Basic information
Biomarker: mPRβ
Biomarker subtype: gene
Clinical application: prognosis(favorable)
Histology type: endometrial carcinoma
Cohort characteristics
Region: Slovenia
Cohort age: 62.5±13.6
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 50 | EC | 50 |
Sample information
Sample type : tissue
Clinical method: Quantitative PCR
Disease information
Statictics: Mean (SD)
Cohort age: 62.5±13.6
Related information
Description: Membrane progesterone receptors β has potential as prognostic biomarkers of endometrial cancer.
Approved symbol: PAQR8
Approved name: progestin and adipoQ receptor family member 8
Locus type: gene with protein product
HGNC ID: HGNC:15708
HGNC link: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:15708
Symbol status: Approved
Previous symbols: C6orf33
Alias symbols: LMPB1 MPRB
OMIM: 607780
Omim link: https://www.omim.org/entry/607780
NCBI name: 85315
NCBI link: https://www.ncbi.nlm.nih.gov/gene/85315
Summary: Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in brain (RPKM 26.8), colon (RPKM 23.1) and 21 other tissues
NCBI gene expression https://www.ncbi.nlm.nih.gov/gene/85315#gene-expression
PDB ID: Q8TEU7
PDB link: https://www.ebi.ac.uk/pdbe/entry/search/index/?searchParams=%7B%22text%22:%5B%7B%22value%22:%22Q8TEZ7%22,%22condition1%22:%22AND%22,%22condition2%22:%22Contains%22%7D%5D,%22resultState%22:%7B%22tabIndex%22:0,%22paginationIndex%22:1,%22perPage%22:%2210%22,%22sortBy%22:%22Sort%20by%22%7D%7D
