Basic information
Biomarker: rs1137101
Biomarker subtype: gene
Clinical application: prognosis(protective factor in the development of endometrial cancer)
Histology type: endometrial carcinoma
Cohort characteristics
Country: Poland
Region: Lodz
Followed up time : NA
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 210 | endometrial cancer | 120 | uterine fibroids | 90 |
Sample information
Sample type : tissue
Clinical method: RT-qPCR
Expression pattern : heterozygous genotype AG of SNP LEP-R c.668A>G
Disease information
Related information
Description: AG polymorphic variant of SNP LEP-R c.668A>G (p.Gln223Arg, rs1137101) in LEP-R may be considered a protective factor in the development of endometrial cancer.
Expression figure legend: Distribution of genotypes and alleles of SNP LEP-R c.668A>G (p.Gln223Arg, rs1137101) in obese Cases (TG3) and lean Controls (C1)
Expression figure link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369646/figure/Fig3/
