Basic information
Biomarker: DNA ploidy
Biomarker subtype: gene
Clinical application: prognosis
Histology type: endometrial carcinoma
Cohort characteristics
Country: Turkey
Region: Trabzon
| Total number | Group I | Group I number | Group II | Group II number | Group III | Group III number | Group IV | Group IV number |
|---|---|---|---|---|---|---|---|---|
| 136 | Tumor material | 136 |
Sample information
Sample type : tissue
Clinical method: immunohistochemistry/image cytometry
Disease information
Related information
Description: However, since p53 or DNA ploidy were found to be significant factors in univariate analysis and were correlated with tumor recurrence, they could be useful factors in making prognoses.
Detailed Description: Ploidy is the number of complete sets of chromosomes in a cell, and hence the number of possible alleles for autosomal and pseudoautosomal genes. Sets of chromosomes refer to the number of maternal and paternal chromosome copies, respectively, in each homologous chromosome pair, which chromosomes naturally exist as. Somatic cells, tissues, and individual organisms can be described according to the number of sets of chromosomes present (the "ploidy level"): monoploid (1 set), diploid (2 sets), triploid (3 sets), tetraploid (4 sets), pentaploid (5 sets), hexaploid (6 sets), heptaploid[doi:10.1007/bf00119108] or septaploid[3] (7 sets), etc. The generic term polyploid is often used to describe cells with three or more chromosome sets.[doi:10.1007/978-3-642-96327-8][Darlington, C. D. (Cyril Dean) (1937). Recent advances in cytology. Philadelphia: P. Blakiston's son & co. p. 60.]
